Breakthrough could lead to early detection of pregnancy complications

Breakthrough could lead to early detection of pregnancy complications
Researchers have found a way to study uterine fluid in the lab, thereby avoiding invasive procedures during pregnancy, while at the same time developing a potential model for using precision medicine to improve pregnancy outcomes.

Gene therapy restores immune function in children with rare immunodeficiency

Gene therapy restores immune function in children with rare immunodeficiency
An investigational gene therapy can safely restore the immune systems of infants and children who have a rare, life-threatening inherited immunodeficiency disorder, according to new research. The researchers found that 48 of 50 children who received the gene therapy retained their replenished immune system function two to three years later and did not require additional treatments for their condition,...

Researchers develop new biomaterial that helps bones heal faster

Researchers develop new biomaterial that helps bones heal faster
Scientists have developed a new biomaterial that helps bones heal faster by enhancing adults’ stem cell regenerative ability.

Molecular analysis identifies key differences in lungs of cystic fibrosis patients

Molecular analysis identifies key differences in lungs of cystic fibrosis patients
A team of researchers has developed a molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis.

Stem cells create early human embryo structure in advance for fertility research

Stem cells create early human embryo structure in advance for fertility research
Stem cells have the ability to turn into different types of cell. Now scientists have developed a method to organize lab-grown stem cells into an accurate model of the first stage of human embryo development.

Restricting growth, spread of head and neck cancers

Restricting growth, spread of head and neck cancers
Researchers have discovered a key molecule that allows cancer stem cells to bypass the body’s natural immune defenses, spurring the growth and spread of head and neck squamous cell cancers. Their study, conducted in mice, also demonstrates that inhibiting this molecule derails cancer progression and helps eliminate these stem cells.

Comprehensive single-cell atlas of human teeth

Comprehensive single-cell atlas of human teeth
Researchers have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.

Scientists reveal how brain cells in Alzheimer’s go awry, lose their identity

Scientists reveal how brain cells in Alzheimer's go awry, lose their identity
Despite the prevalence of Alzheimer’s, there are still no treatments, in part because it has been challenging to study how the disease develops. Now, scientists have uncovered new insights into what goes awry during Alzheimer’s by growing neurons that resemble — more accurately than ever before — brain cells in older patients. And like patients themselves, the afflicted neurons...

Muscle gene linked to type 2 diabetes

Muscle gene linked to type 2 diabetes
People with type 2 diabetes tend to have poorer muscle function than others. Now a research team has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells.

Recreating the earliest stages of life

Recreating the earliest stages of life
A group of scientists has now demonstrated the presence of precursors of the placenta and the amniotic sac in synthetic embryos they created from mouse stem cells.