Scientists use nanotechnology to detect bone-healing stem cells

Scientists use nanotechnology to detect bone-healing stem cells
Researchers have developed a new way of using nanomaterials to identify and enrich skeletal stem cells — a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.

Cellular benefits of gene therapy seen decades after treatment

Cellular benefits of gene therapy seen decades after treatment
Researchers have shown that the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells has been cleared by the body.

Double trouble for drug-resistant cancers

Double trouble for drug-resistant cancers
New research identifies chemotherapy-resistant cancers’ escape mechanism, which offers new anti-cancer treatment options.

Treatment for type-2 diabetic heart disease

Treatment for type-2 diabetic heart disease
Researchers have discovered one of the reasons why more than 50 per cent of people with type 2 diabetes die from heart disease. And perhaps more significantly, they have found a way to treat it.

Single cell sequencing opens new avenues for eradicating leukemia at its source

Single cell sequencing opens new avenues for eradicating leukemia at its source
Cancer stem cells that elude conventional treatments like chemotherapy drive long-term cancer growth and relapse. These cells are difficult to isolate and study because of their low abundance and similarity to other stem cells. Researchers have created a new method that can distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression....

Researchers identify mechanisms that are essential for proper skin development

Researchers identify mechanisms that are essential for proper skin development
Latest discovery could improve development of future stem cell therapies and cancer treatments.

Unlocking the mystery behind skeletal aging

Unlocking the mystery behind skeletal aging
Researchers have identified the role a critical enzyme plays in skeletal aging and bone loss, putting them one step closer to understanding the complex biological mechanisms that lead to osteoporosis, the bone disease that afflicts some 200 million people worldwide. Findings could hold an important key to developing more effective treatments for osteoporosis and improving the lives of an aging population....

Scientists discover a new pathway essential for blood formation

Scientists discover a new pathway essential for blood formation
Scientists have discovered how a protein called Tip60 plays a vital role in the renewal of blood cells in the body. Without it, the stem cells that make new blood suffer catastrophic damage. This discovery could lead to better treatments for life-threatening blood-related diseases like leukemia.

Hematopoietic stem cell transplants may provide long-term benefit for people with MS

Hematopoietic stem cell transplants may provide long-term benefit for people with MS
A new study shows that intense immunosuppression followed by a hematopoietic stem cell transplant may prevent disability associated with multiple sclerosis (MS) from getting worse in 71% of people with relapsing-remitting MS for up to 10 years after the treatment. The study also found that in some people their disability improved over 10 years after treatment.

The bull’s eye: New modified stem cells can deliver drugs specifically to tumor cells

The bull's eye: New modified stem cells can deliver drugs specifically to tumor cells
Targeting drugs to cancer tissues is a major challenge in cancer treatment. Mesenchymal stem cells (MSCs) are known for their ability to find and target tumor cells in the body, but using MSCs for drug delivery has been tricky, because upon loading with drugs, MSCs lose their viability and migratory ability. Now, researchers have successfully modified MSCs to deliver large quantities of anti-cancer...