Nw study findings implicate a specific type of immune cell behind heterotopic ossification, or abnormal bone formation and present a possible target for treatment.

New research has deciphered how rogue communications in blood stem cells can cause leukemia. The discovery could pave the way for new, targeted medical treatments that block this process.

Researchers have reported the use of a stem cell gene therapy to treat nine people with the rare, inherited blood disease known as X-linked chronic granulomatous disease, or X-CGD. Six of those patients are now in remission and have stopped other treatments. Before now, people with X-CGD – which causes recurrent infections, prolonged hospitalizations for treatment, and a shortened lifespan —...

Researchers have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment. The next step is to perform extensive safety tests in rodents and pigs, and then move to human patients suffering chronic pain within the next five years.

Researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system. Using human induced pluripotent stem cells, this novel approach combined a variety of techniques that enabled the development of three-dimensional groups of intestinal cells called organoids...

A drug designed to tackle diabetes could also be repurposed as the first treatment to prevent miscarriage by targeting the lining of the womb itself, according to a clinical trial.

Patients with well-supported immune cells in their tumors are more likely to control their cancers’ growth for a longer time, an observation that could guide treatment decisions after surgery for kidney cancer. In addition, the findings could help researchers expand the dramatic but sparse benefits of cancer immunotherapy to more people.

A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified.

Today’s standard process for administering gene therapy is expensive and time-consuming — a result of the many steps required to deliver the healthy genes into the patients’ blood stem cells to correct a genetic problem. Scientists believe they have found a way to sidestep some of the current difficulties, resulting in a more efficient gene delivery method that would save money and...

Researchers have demonstrated a new, rapid method to obtain donor stem cells for bone marrow transplants using a combination of Viagra and a second drug called Plerixafor. Bone marrow transplants, used mostly in the treatment of cancer, are life-saving procedures to restore the stem cells that generate new blood cells throughout a person’s life.