Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, says a new study. Researchers found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but — in a surprise to the research team — also induced the regeneration of healthy blood cells.

A team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. The team was surprised to observe that these very aggressive tumors arise from mature, pigment-producing cells called melanocytes. As melanoma develops, these cells are eventually reprogrammed, lose their differentiated features and become invasive, migratory cancer cells. This knowledge...

Researchers have created expanded potential stem cells (EPSCs) in mice, for the first time, that have a greater potential for development than current stem cell lines. These stem cells have the features of the very first cells in the developing embryo, and can develop into any type of cell.

For the first time, research shows that glioblastoma (GBM) is driven by two distinct subsets of cancer stem cells. Moreover, each subtype of glioma stem cells is driven by distinct transcriptional programs for growth and treatment resistance. The subsets also responded better to combination treatment in the mouse model.

A new study has used flat worms to look at the role of migrating stem cells in cancer. Researchers used the worms (planarians) which are known for their ability to regenerate their tissues and organs repeatedly. By understanding how stem cells are programmed to move, what activates them and how they follow a correct path, researchers may be able to design new treatments for cancer.

Intravenous stem cell infusion derived from umbilical cords appears to boost heart muscle function in patients with heart failure, according to a small study. In this first-of-its-kind study, patients had ‘significant’ improvement in their hearts’ ability to pump blood and experienced no adverse side effects related to the therapy. The results suggest IV-infused umbilical cord-derived...

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