An index measures similarity between cancer cells and pluripotent stem cells

An index measures similarity between cancer cells and pluripotent stem cells
The new methodology measures tumor aggressiveness and the risk of relapse, helping doctors plan treatment.

Anemia: When cells fail to produce enough protein factories

Anemia: When cells fail to produce enough protein factories
Every day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers have succeeded in furthering our understanding of how blood cells are formed. Their insights into the molecular foundations of this process may help break new ground in the treatment of certain types of anemia.

Mesenchymal stem cell therapy: Holding promise for feline inflammatory diseases

Mesenchymal stem cell therapy: Holding promise for feline inflammatory diseases
Stem cell therapy is acknowledged as having great potential for the treatment of a variety of diseases in both people and animals. The use of bone marrow-derived stem cells is well established in the treatment of human cancer patients, and veterinary applications for bone marrow- and adipose-derived stem cells are being evaluated.

Personalized stem cell treatment may offer relief for multiple sclerosis

Personalized stem cell treatment may offer relief for multiple sclerosis
Scientists have shown in mice that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by multiple sclerosis (MS).

Versatile sensor against tumor initiating cells

Versatile sensor against tumor initiating cells
Researchers have developed the first fluorescent sensor to visualize TICs. Functional in lung, central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer cell cultures, this could become a useful tool for biopsy-free post-treatment assessment and anti-TIC drug development.

Scientists target glioma cancer stem cells, which could improve patient survival

Scientists target glioma cancer stem cells, which could improve patient survival
Brain tumors are responsible for 25 percent of cancer-related deaths in children and young adults. Despite initial response to treatment, most aggressive brain tumors eventually recur and are ultimately incurable. Multiple studies suggest that cancer stem cells within these tumors resist therapy and are responsible for tumor recurrences. Researchers have devised a strategy to treat these tumors by...

Study could explain link between high-cholesterol diet and colon cancer

Study could explain link between high-cholesterol diet and colon cancer
Scientists discovered that boosting mice’s cholesterol levels spurred intestinal stem cells to divide more quickly, enabling tumors to form 100 times faster. The study identifies a molecular pathway that could serve as a new drug target for colon cancer treatment.

Prader-Willi syndrome reversed in brain cells growing in the lab

Prader-Willi syndrome reversed in brain cells growing in the lab
Stem cell researchers have reversed Prader-Willi syndrome in brain cells growing in the lab. The discovery provides clues that could lead to a treatment for Prader-Willi, a genetic disorder that silences genes necessary for normal brain function. Prader-Willi occurs in about one out of every 15,000 births, and is the most common genetic cause of life-threatening childhood obesity.

Discovery may advance neural stem cell treatments for brain disorders

Discovery may advance neural stem cell treatments for brain disorders
New research reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease, Parkinson’s disease, and mental health disorders that affect cognitive abilities.

Hedgehog signaling proteins keep cancer stem cells alive

Hedgehog signaling proteins keep cancer stem cells alive
Scientists have discovered that the survival of cancer stem cells is dependent on the ‘Hedgehog signaling pathway’. Targeting this pathway had previously shown no effect on the growth of colorectal cancer. Now, scientists have demonstrated that using different drugs to target a specific aspect of the pathway may yield better treatment outcomes for patients.