Scientists believe they have uncovered an ‘Achilles heel’ of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer. Their study details how a mechanism that protects glioma stem cells can potentially be exploited to develop new and more effective treatments for GBM.

A researcher uncovered new mechanisms that dictate the development of germline stem cells. Mechanisms were found to be associated with genes responsible for cancers and viral infections among other major diseases. Markers used to identify male germ cells were discovered, exploring how environmental factors or epigenetics affect these cells and providing significant insight into treatments for male...

Doctors have cured seven adult patients of sickle cell disease, an inherited blood disorder primarily affecting the black community, using stem cells from donors previously thought to be incompatible, thanks to a new transplant treatment protocol.

Medical researchers have designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to...

The new methodology measures tumor aggressiveness and the risk of relapse, helping doctors plan treatment.

Every day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers have succeeded in furthering our understanding of how blood cells are formed. Their insights into the molecular foundations of this process may help break new ground in the treatment of certain types of anemia.

Researchers have developed the first fluorescent sensor to visualize TICs. Functional in lung, central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer cell cultures, this could become a useful tool for biopsy-free post-treatment assessment and anti-TIC drug development.

Brain tumors are responsible for 25 percent of cancer-related deaths in children and young adults. Despite initial response to treatment, most aggressive brain tumors eventually recur and are ultimately incurable. Multiple studies suggest that cancer stem cells within these tumors resist therapy and are responsible for tumor recurrences. Researchers have devised a strategy to treat these tumors by...