Diabetic blindness: Best source of stem cells to block vision loss

Diabetic blindness: Best source of stem cells to block vision loss
Stem cells taken from donors are more likely to be more effective at battling diabetic retinopathy than cells taken from patients’ own bodies, a new study concludes. The work is a critical step toward the goal of injecting stem cells into patients’ eyes to stop or even reverse the vision loss. The findings also establish a crucial framework for evaluating stem cells to be used in potential...

Discovery promises new treatments to thwart colon cancer

Discovery promises new treatments to thwart colon cancer
Scientists have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells. Surprisingly, they also discovered that AIM2 influences the microbiota — the population of gut bacteria — apparently fostering the proliferation...

Bioengineered patch, molecular ‘booster’ could improve stem cells’ ability treat heart failure

Bioengineered patch, molecular 'booster' could improve stem cells' ability treat heart failure
Despite the intense activity and high hopes that surround the use of stem cells to reverse heart disease, scientists still face multiple roadblocks before the treatment will be ready for clinical prime time. Researchers are now finding ways to maximize the healing potential of stem cells by helping them overcome the inhospitable conditions of a damaged heart – bringing the promise of stem cell therapy...

Better than stem cells: Researchers develop a faster way to treat the heart after a heart attack

Better than stem cells: Researchers develop a faster way to treat the heart after a heart attack
For healing the heart after a heart attack, stem cell therapies show promise but are slow to implement. Researchers develop a new treatment called microsphere therapy that can be kept on-hand and administered more readily than stem cells.

Nanoparticles target and kill cancer stem cells that drive tumor growth

Nanoparticles target and kill cancer stem cells that drive tumor growth
Many cancer patients survive treatment only to have a recurrence within a few years. Recurrences and tumor spreading are likely due to cancer stem cells that can be tough to kill with conventional cancer drugs. But now researchers have designed nanoparticles that specifically target these hardy cells to deliver a drug. The nanoparticle treatment worked far better than the drug alone in mice.

Mini-breasts grown in petri dishes

Mini-breasts grown in petri dishes
About 70,000 Women are diagnosed with breast cancer every year in Germany alone. Despite significant progress in the treatment of common types of breast cancer, some aggressive subtypes are poorly understood and remain incurable. A new experimental model opens new avenues for mammary gland biology and basic breast cancer research. Researchers are now able to create three-dimensional organoid-structures...

Potential new treatment for osteoporosis

Potential new treatment for osteoporosis
Scientists have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming cells in patients suffering from bone loss.

Scientists find way to disrupt brain tumor stem cells

Scientists find way to disrupt brain tumor stem cells
Brain tumor stem cells can resist treatment and regrow tumors, but scientists have identified a vulnerability in these cells that could lead to a new approach in battling deadly brain tumors.

Stem cell discovery paves way for targeted treatment for osteoarthritis

Stem cell discovery paves way for targeted treatment for osteoarthritis
Scientists have made a significant advance that could make cell-based treatments for arthritis less of a lottery. Researchers have identified individual stem cells that can regenerate tissue, cartilage and bone.

Recovery of sensory function by stem cell transplants

Recovery of sensory function by stem cell transplants
New research shows promising progress in the use of stem cells for treatment of spinal cord injury. The results show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.