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Skin stem cells get moving for enhanced skin regeneration

Researchers have found that the ability of skin stem cells to heal wounds is linked with their ability to move towards the injury. Their study identified the signalling pathway of EGFR and COL17A1 as a key player in the regulation of motility. Understanding mechanisms that underlie the age-associated reduction in regenerative capacity is the first step to develop targeted treatments for age-associated...
Developing a treatment for vision loss through transplant of photoreceptor precursors

A recent study examining the therapeutic potential of photoreceptor precursors, derived from clinically compliant induced pluripotent stem cells (iPSC), has demonstrated the safety and therapeutic potential of clinically compliant iPSC-derived photoreceptor precursors as a cell replacement source for future clinical trials.
Power of stem cells harnessed to create cartilage tissue

Researchers have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage.
Researchers explore promising treatment for MRSA ‘superbug’

A new study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.
Stem-like T cells could aid immunotherapy in cancer treatment

Researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.
Fighting brain cancer at its root

Researchers identify proteins that drive cancer stem cells. Targeting and suppressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.
Researchers discover key stem cell dormancy mechanism which could help unlock future cancer treatments

Researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.
Stem cells can use same method as plants and insects to protect against viruses

Researchers have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. The scientists suggest this could one day be exploited in the development of new antiviral treatments.
Muscles retain positional memory from fetal life

Muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This positional memory was found to be based on the expression pattern of the homeobox (Hox) gene cluster, which is responsible for shaping the body during fetal life. These findings are expected to provide clues to elucidate the pathogenesis of muscle diseases like...
Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

Biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment.