Still more blind can be cured

Still more blind can be cured
A number of illnesses causing blindness can be cured from transplanting cells from the oral cavity. New findings make the treatment accessible to the places where the condition strikes the most frequently: in developing countries.

Viral infection in colon cancer stem cells mimicked; druggable target identified

Viral infection in colon cancer stem cells mimicked; druggable target identified
Researchers targeting colorectal cancer stem cells – the root cause of disease, resistance to treatment and relapse – have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.

How newts can help osteoarthritis patients

How newts can help osteoarthritis patients
Osteoarthritis is the most common form of joint disease worldwide. Now, scientists have taken a leaf out of nature’s book in an attempt to develop effective stem cell treatment for osteoarthritis, a condition which affects millions of people in the UK alone.

Precision medicine brought one step closer to the clinic

Precision medicine brought one step closer to the clinic
A revolutionary, high-throughput, robotic platform has been designed that automates and standardizes the process of transforming patient samples into stem cells. This unique platform for the first time gives researchers the scale to look at diverse populations to better understand the underlying causes of disease and create new individually tailored treatments, enabling precision medicine in patient...

Muscle fibers grown in the lab offer new model for studying muscular dystrophy

Muscle fibers grown in the lab offer new model for studying muscular dystrophy
Investigators report that they have been able to drive cells to grow into muscle fibers, producing millimeter-long muscle fibers capable of contracting in a dish and multiplying in large numbers. This new method of producing muscle cells could offer a better model for studying muscle diseases, such as muscular dystrophy, and for testing out potential treatment options.

Scientists identify gene vital for rebuilding intestine after cancer treatment

Scientists identify gene vital for rebuilding intestine after cancer treatment
A rare type of stem cell is immune to radiation damage thanks to high levels of a gene called Sox9, researchers have discovered.

New drug for blood cancers now in five phase II clinical trials

New drug for blood cancers now in five phase II clinical trials
The safety and dosing of a new drug for treating blood cancers has now been established by a group of scientists. The drug is a small molecule inhibitor that suppresses the activity of a signaling pathway believed to contribute to a variety of blood cancers’ eventual resistance to standard chemotherapy treatments.

Opening the door to the cause of myeloid leukemia: Finding the targets of common mutation

Opening the door to the cause of myeloid leukemia: Finding the targets of common mutation
Professor Peter Cockerill, of the University of Birmingham, explained: “We found that the mutated FLT3 protein always sends the same signals to the same set of genes in all AML patients that have this mutation. By finding out which signals and genes are the targets, we now have new targets that will allow us to attack this pathway.” Researchers at the University of Birmingham have made...

Prostate cancer: Scientists discover why some tumous are resistant to radiotherapy

Prostate cancer: Scientists discover why some tumous are resistant to radiotherapy
It is hoped that this new development could pave the way for more effective treatments — allowing a lower dose of radiotherapy to be used while prolonging the lives of thousands of men. In the latest studies, published in European Urology and the British Journal of Cancer, scientists in The YCR Cancer Research Unit in the Department of Biology at York have shown a direct link between these tiny...

New material forges the way for ‘stem cell factories’

New material forges the way for 'stem cell factories'
If you experience a major heart attack the damage could cost you around five billion heart cells. Future stem cell treatments will require this number and more to ensure those cells are replaced and improve your chances of survival.