Pillar of support: Breakthrough discovery could speed up bone implant recovery

Pillar of support: Breakthrough discovery could speed up bone implant recovery
A research team has uncovered a new technique that can speed up recovery from bone replacements. Novel micropillars, 10 times smaller than the width of a human hair, can change the size, shape and nucleus of individual stem cells and ‘trick’ them to become bone. Further research will look to improve the process of locking bone replacements with reduced risk of infection.

New insight into formation of the human embryo

New insight into formation of the human embryo
Pioneering research led has provided new insight into formation of the human embryo.

New method expands the world of small RNAs

New method expands the world of small RNAs
Biomedical scientists have developed a new RNA-sequencing method — ‘Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing,’ or PANDORA-seq — that can help discover numerous modified small RNAs that were previously undetectable.

Tadpole nerve regeneration capacity provides clue to treating spinal cord injury

Tadpole nerve regeneration capacity provides clue to treating spinal cord injury
Researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration. Their study showed that introducing the gene into mice with spinal cord injury (SCI) led to a partial recovery of their lost motor functions.

Regenerating hair follicle stem cells

Regenerating hair follicle stem cells
Researchers have identified the biological mechanism of how chronic stress leads to hair loss. They found that the stress hormone corticosterone causes hair follicle stem cells to stay in an extended resting phase, without regenerating tissue. The stress signal was first received by dermal cells surrounding the hair follicle, preventing them from releasing Gas6, a molecule that activates stem cells....

Scientists use nanotechnology to detect bone-healing stem cells

Scientists use nanotechnology to detect bone-healing stem cells
Researchers have developed a new way of using nanomaterials to identify and enrich skeletal stem cells — a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.

Chemical cocktail creates new avenues for generating muscle stem cells

Chemical cocktail creates new avenues for generating muscle stem cells
A research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.

New bioink brings 3D-printing of human organs closer to reality

New bioink brings 3D-printing of human organs closer to reality
Researchers have designed a new bioink which allows small human-sized airways to be 3D-bioprinted with the help of patient cells for the first time. The 3D-printed constructs are biocompatible and support new blood vessel growth into the transplanted material. This is an important first step towards 3D-printing organs.

Cellular benefits of gene therapy seen decades after treatment

Cellular benefits of gene therapy seen decades after treatment
Researchers have shown that the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells has been cleared by the body.

HSC transplants in embryos: Opening the door for hematopoiesis research

HSC transplants in embryos: Opening the door for hematopoiesis research
Researchers describe a new technique for hematopoietic stem cell transplantation in embryos that does not require destroying host hematopoietic system.